Research Information System
4TH INTERNATIONAL CONGRESS ON ADVANCES IN VETERINARY SCIENCES AND TECHNİCS, Kyyiv, Ukraine, 10 - 14 July 2019, pp.2
Aim: Flaxseed is an important plant grown worldwide. Most of the observed benefits and the
preventive properties related to illnesses have been attributed to its Omega-3 fatty acid and αlinoleic content. Due to the high cost of drugs, people resort to alternative medication to treat
diabetes and other diseases. Flaxseed was usually studied in diabetic patients and decreased the
amount of insulin. Studies mostly focuses on the positive effects of flaxseed. Very few studies are
aimed investigate harmful effect of flaxseed. The purpose of this study was to investigate negative
effects of flaxseed on short-term and more than necessary consumption on pancreas tissues.
Material and methods: In our study, 32 female Wistar rats were used; Group I; control (n: 8, given
drinking water every day with gavage), Group II (Low-dose flaxseed group; 1,4 mg / g flaxseed
gavage daily for 7 days) Group III (Medium-dose flaxseed group; 2,8mg / g flaxseed gavage every day
for 7 days), Group IV (High-dose flaxseed group; 5,6mg / g flaxseed was given by gavage every day
for 7 days) and grouped. Results: At the end of the experiment, the pancreas tissue was taken by
histochemical analysis and stained with H-E and examined under a microscope. No histopathological
findings were observed in the control group. In the experimental group (group IV) given flaxseed,
shrinkage in langerhans islets, mononuclear cell infltrasions and in some area; hemorrhagecongestion was observed when compared to the control group. Conclision: Flaxseed cause damage
to the pancreas tissue in the case of short-term and more than necessary consumption. In this sense,
we believe that our study will lead other studies for time and dose of the experiments