Is nitric oxide involved in the pathophysiology of essential hyperhidrosis?

Karaca S., Kulac M., Uz E. , Barutcu I., Yilmaz H. R.

INTERNATIONAL JOURNAL OF DERMATOLOGY, cilt.46, ss.1027-1030, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 10
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1365-4632.2007.03243.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF DERMATOLOGY
  • Sayfa Sayısı: ss.1027-1030

Özet

Background Essential hyperhidrosis (EH) is a disorder of excessive, bilateral, and relatively symmetric sweating occurring in the axillae, palms, soles, or craniofacial region without obvious etiology. The expression of endothelial nitric oxide synthase (eNOS) in eccrine clear cells, reported by an immunohistochemical technique, has suggested that nitric oxide (NO) may play a role in the physiology of production and/or excretion of sweat in the human skin eccrine gland.