Iron and cobalt co-doped ZnO nanoparticles grafted over CNTs: An efficient electrochemical probe for the detection of paracetamol
DIAMOND AND RELATED MATERIALS, cilt.163, ss.1-12, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 163
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.diamond.2026.113367
- Dergi Adı: DIAMOND AND RELATED MATERIALS
- Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), Chemical Abstracts Core, Chimica, Compendex, INSPEC
- Sayfa Sayıları: ss.1-12
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Acetaminophen (paracetamol), a widely used analgesic and antipyretic, requires precise and sensitive detection for pharmaceutical and clinical applications. Iron and Cobalt (Fe/Co) co-doped ZnO@CNTs nanocomposites, synthesized via a precipitation method has been developed for the electrochemical detection of acetaminophen. These nanocomposites were doped with equimolar amount of Fe/Co with the concentrations of 1%, 5%, and 10% to optimize the electrocatalytic performance of nanocomposites (ZnO@CNTs). Characterization using Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) Energy-Dispersive X-ray Spectroscopy (EDX), and X-ray Diffraction (XRD) and Raman spectroscopy confirmed the successful metallic doping and uniform dispersion within the composite matrix. While, electrochemical studies, including cyclic voltammetry (CV), scan rate analysis, and chronoamperometry, revealed that the 1% doped concentration achieved the lowest limit of detection (LOD), significantly enhancing electron transfer kinetics and sensitivity for acetaminophen detection. 1% Fe/Co doped ZnO@CNT showed lowest LOD of 0.045 μM with high sensitivity of 1.862 μA mM−1 cm−2. The Fe/Co-doped ZnO@CNTs nanocomposites demonstrated outstanding sensitivity, stability, and reproducibility, underscoring their potential for practical acetaminophen analysis.