Roles of Medicinal Plants and Constituents in Gynecological Cancer Therapy: Current Literature and Future Directions


AKKOL E., Dereli F. T. , Sobarzo-Sanchez E., Khan H.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol.20, no.20, pp.1772-1790, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 20 Issue: 20
  • Publication Date: 2020
  • Doi Number: 10.2174/1568026620666200416084440
  • Title of Journal : CURRENT TOPICS IN MEDICINAL CHEMISTRY
  • Page Numbers: pp.1772-1790
  • Keywords: Gynecological oncology, Medicinal plant, Drug molecule, Cancer, Natural product, Female reproductive system, SENTINEL LYMPH-NODE, RECURRENT OVARIAN-CANCER, EARLY CERVICAL-CANCER, I CLINICAL-TRIAL, ENDOMETRIAL CANCER, NATURAL-PRODUCTS, MULTIDRUG-RESISTANCE, RADIATION-THERAPY, BETULINIC ACID, BISBENZYLISOQUINOLINE ALKALOIDS

Abstract

Gynecologic cancers, including cervical, primary peritoneal, ovarian, uterine/endometrial, vaginal and vulvar cancers and gestational trophoblastic disease, are characterized by abnormal cell proliferation in female reproductive cells. Due to the variable pathology of these cancers and the lack of appropriate screening tests in developing countries, cancer diagnosis can be reported in advanced stages in most women and this situation adversely affects prognosis and clinical outcomes of illness. For this reason, many researchers in the field of gynecological oncology have carried out many studies.