Sudden Death in Hemodialysis: An Update


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Kanbay M., Afsar B. , Goldsmith D., Covic A.

BLOOD PURIFICATION, vol.30, no.2, pp.135-145, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 30 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1159/000320370
  • Title of Journal : BLOOD PURIFICATION
  • Page Numbers: pp.135-145

Abstract

Cardiovascular disease including sudden death, myocardial infarction, cardiac arrest, malignant arrhythmias and other cardiac causes is the major cause of death accounting for 43% of all-cause mortality among hemodialysis patients. In addition to increased traditional risk factors, hemodialysis patients also have a number of nontraditional cardiovascular risk factors, which may play a prominent role in the development of sudden death such as left ventricular hypertrophy, coronary artery disease, rapid electrolyte shifts, QT dispersion, sympathetic overactivity, calcium-phosphate deposition. The purpose of the present review was to critically review the current literature to summarize the following aspects: (1) the pathophysiological mechanism responsible for sudden death in hemodialysis patients, and (2) the prevention and management of sudden death in hemodialysis patients. Copyright (C) 2010 S. Karger AG, Basel