ARCHIVES OF ORAL BIOLOGY, vol.81, pp.61-68, 2017 (SCI-Expanded)
Article / Article
ARCHIVES OF ORAL BIOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Caffeic acid phenethyl ester-CAPE, Doxycycline, Periodontitis, Cytokines, Oxidative stress, Apoptosis, ALVEOLAR BONE LOSS, NECROSIS-FACTOR-ALPHA, LOW-DOSE DOXYCYCLINE, FACTOR-KAPPA-B, ISCHEMIA/REPERFUSION INJURY, OXIDATIVE DAMAGE, RATS, APOPTOSIS, DISEASE, MODEL
Süleyman Demirel University Affiliated:
Background and objectives: Host modulation therapies (anti-inflammatory drugs, bone-stimulating agents, antiproteinase etc.) target the inhibition or stabilization of tissue breakdown. The aim of the present study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) and/or low dose doxycycline (LDD) administrations on alveolar bone loss (ABL), serum cytokines and gingival apoptosis, as well as the levels of oxidants and antioxidants in rats with ligature-induced periodontitis.