MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, vol.825, pp.15-18, 2018 (SCI-Expanded)
Article / Article
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Silybum marianum, Silmarin, Comet assay, COMET ASSAY, OXIDATIVE STRESS, INDIVIDUAL CELLS, IN-VITRO, ANTIOXIDANT, MELLITUS, SILYBIN, REPAIR, HYPERGLYCEMIA, BIOMARKERS
Süleyman Demirel University Affiliated:
Silibinin, the active component of Silybum marianum (L.), is a powerful antioxidant. Male rats with streptozotocin-induced diabetes were treated with silibinin. DNA damage was demonstrated by the comet assay in the control, diabetic, and treatment groups. DNA damage was increased in diabetic rats and decreased by silibinin treatment.