Research Information System
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.11, no.1, pp.28-32, 2020 (ESCI)
Aim: The long-term survival in Non-Small Cell Lung Cancer (NSCLC) following tumor-free resection is less than fifty percent. The most important cause affecting the mortality following the resection is the development of recurrence. This study aims to determine the factors affecting the recurrence, to increase the awareness concerning this topic and to enlighten this challenge by virtue of new studies. Material and Method: In this study, the data were obtained by studying retrospectively the database of the patients who underwent complete resection due to the NSCLC between January 2008 and December 2012 in our Thoracic Surgery Clinic. The effects of the clinicopathologic variables on the distant recurrence were assessed. Results: Fifty male patients (87.7%) and seven female patients (12.3%) with NSCLC were included in the study. Distant recurrence was developed in seven of the patients. During the three-year follow-up, we obtained statistically significant values in comparing the parameters affecting the survival such as differentiation (p=0.012), pathological stage (p=0.02), development of distant recurrence (p=0.014), the location of the distant recurrence (p=0.011), the duration spent in the intensive care unit (p=0.018), the length of stay (p=0.018) and the time for the postoperative distant recurrence (0.048). A statistical significance was detected between the distant recurrence and the hilar lymphadenopathies larger than one centimeter in computerized tomography (p=0.049). Discussion: We found that the presence of the hilar lymphatic node larger than one centimeter in computerized tomography is the most important parameter in the development of distant recurrence.