Current status of micro/nanomotors in drug delivery


Tezel G. , TİMUR S. S. , KURALAY F., GÜRSOY R. N. , ULUBAYRAM K., ÖNER L., ...More

JOURNAL OF DRUG TARGETING, vol.29, no.1, pp.29-45, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 29 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1080/1061186x.2020.1797052
  • Title of Journal : JOURNAL OF DRUG TARGETING
  • Page Numbers: pp.29-45
  • Keywords: Micro, nanomotor, propulsion, drug delivery, nanotechnology, biodegradation, SOLID LIPID NANOPARTICLES, STOMATOCYTE NANOMOTORS, INTRACELLULAR DELIVERY, CATALYTIC NANOMOTORS, MICROMOTORS DRIVEN, AUTONOMOUS MOTION, JANUS MICROMOTORS, SILICA NANOMOTORS, HYALURONIC-ACID, NANO-MOTORS

Abstract

Synthetic micro/nanomotors (MNMs) are novel, self-propelled nano or microscale devices that are widely used in drug transport, cell stimulation and isolation, bio-imaging, diagnostic and monitoring, sensing, photocatalysis and environmental remediation. Various preparation methods and propulsion mechanisms make MNMs "tailormade" nanosystems for the intended purpose or use. As the one of the newest members of nano carriers, MNMs open a new perspective especially for rapid drug transport and gene delivery. Although there exists limited number ofin-vivostudies for drug delivery purposes, existence ofin-vitrosupportive data strongly encourages researchers to move on in this field and benefit from the manoeuvre capability of these novel systems. In this article, we reviewed the preparation and propulsion mechanisms of nanomotors in various fields with special attention to drug delivery systems.