The role of circulating miR-200 family members in differentiating prostate cancer from benign prostatic hyperplasia Mir-200 family in prostate cancer

Ozseven S., Ozturk K., ÖZORAK A.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.12, no.9, pp.1016-1020, 2021 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 9
  • Publication Date: 2021
  • Doi Number: 10.4328/acam.20562
  • Journal Name: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.1016-1020
  • Keywords: Prostate Cancer, Benign Prostate Hyperplasia, microRNA, microRNA-200 Family, MICRORNAS, MIR-141, EXPRESSION
  • Süleyman Demirel University Affiliated: Yes

Abstract

Aim: Although prostate-specific antigen (PSA) is one of the best-known tumor markers used in the early diagnosis of prostate cancer, it may be insufficient in differentiating benign prostatic hyperplasia (BPH) from prostate cancer (PCa). In this study, in cases where the diagnostic power of PSA is insufficient, it was aimed to evaluate the possible diagnostic and prognostic roles of the miR-200 family (miR-200a, miR-200b, miR-200c, miR-141), which has been proven to be associated with cancer by many studies.