Relevance of uric acid and asymmetric dimethylarginine for modeling cardiovascular risk prediction in chronic kidney disease patients

Kanbay, Mehmet; Afsar, Barış; Siriopol, Dimitrie; Unal, Hilmi; Karaman, Murat; Saglam, Mutlu; Eyileten, Tayfun; Gezer, Mustafa; Verim, Samet; Oguz, Yusuf; Vural, Abdulgaffar; Ortiz, Alberto; Johnson, Richard; Covic, Adrian; Yilmaz, Mahmut

doi:10.1007/s11255-016-1271-6

Relevance of uric acid and asymmetric dimethylarginine for modeling cardiovascular risk prediction in chronic kidney disease patients

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Kanbay M., Afsar B., Siriopol D., Unal H. U., Karaman M., Saglam M., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.48, no.7, pp.1129-1136, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 48 Issue: 7
Publication Date: 2016
Doi Number: 10.1007/s11255-016-1271-6
Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1129-1136
Süleyman Demirel University Affiliated: Yes

Abstract

Both elevated serum uric acid and serum asymmetric dimethylarginine (ADMA) are risk factors for cardiovascular disease. We hypothesized that combined elevation of uric acid and ADMA amplifies the risk of all-cause mortality and/or cardiovascular events (CVE) in patients with chronic kidney disease (CKD).