N-functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies


GÖK Y., Akkoc S. , Ozeroglu Celikal O., ÖZDEMİR İ., GÜNAL S., Sayin E.

TURKISH JOURNAL OF CHEMISTRY, cilt.37, ss.1007-1013, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 37 Konu: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3906/kim-1304-72
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.1007-1013

Özet

2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag2CO3 to yield silver(I)-NHC complexes (1a-g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of H-1 NMR, C-13 NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).