In this research, the radiation shielding, structural, mechanical, and acoustic features of the 20BaO-(80-x) Bi2O2-xB(2)O(3) (where x = 70, 60, 50, 40, 30, 20 mol%) glasses are investigated and the obtained results are reported in detail. One of the fundamental parameters in the evaluation of the interaction of radiation with shielding material was the mass attenuation coefficient (MAC) that was obtained using the Phy-X/PSD program in the energy range from 0 to 10 MeV and the calculated results are presented in this paper. Increasing the Bi2O3 concentration changes the composition and density of glass samples and affects the mechanical properties. As a result, the values of elastic moduli such as Young's, Bulk, Shear, and Longitudinal moduli experience a slight reduction. In addition, the Poisson's ratio decreases from 0.27 to 0.17 but the quantity of fractal Bond Connectivity (FBC) increases between 2.26 and 3.59 from BaBiB1 to BaBiB6 glass samples which hints that present glasses have chain structure (3D). Furthermore, the micro-hardness (H) increases from 6.67 to 9.88 GPa with the increase in Bi2O3 concentration. The reported acoustic impedance (Z(i)) increases between 15.16 * 10(3) kg.m(-2) s(-1) and 19.00 *10(3) kg.m(-2) s(-1). The result of this study shows that increasing the amount of Bi2O3 in the preferred glass samples leads to the achievement of high performance radiation shielding materials. Finally, from this research, we can exploit valuable information about the structure of the glass samples.