Modulation of oxidative stress, apoptosis, and calcium entry in leukocytes of patients with multiple sclerosis by Hypericum perforatum
NUTRITIONAL NEUROSCIENCE, cilt.17, sa.5, ss.214-221, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 5
- Basım Tarihi: 2014
- Doi Numarası: 10.1179/1476830513y.0000000083
- Dergi Adı: NUTRITIONAL NEUROSCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.214-221
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Objectives: Hypericum perfortarum (HP, St John's wort) is a modulator of Ca2+ entry in neutrophils and it may modulate intracellular free Ca2+ ([Ca2+](i)) entry in leukocytes of patients with multiple sclerosis (MS). We investigated effects of HP on oxidative stress, apoptosis, and [Ca2+](i) concentrations in serum and leukocytes of patients with MS.