VIRULENCE FACTORS OF PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM CLINICAL SAMPLES AND ROLE OF QUORUM SENSING SIGNAL MOLECULES IN THE PATHOGENESIS OF THE DISEASE

Onal S., ARIDOĞAN B., Gonen I., Tas T., KAYA S.

ACTA MEDICA MEDITERRANEA, vol.31, no.4, pp.851-855, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2015
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.851-855
  • Süleyman Demirel University Affiliated: Yes

Abstract

Introduction: Pathogenicity of Pseudomonas aeruginosa depends on multiple cell-associated factors and virulence factors including "Quorum sensing (QS)" molecules. QS system enables the bacterium to determine the population density around it and the bacterium uses this data to control the regulation of many of its genes. The aim of this study was to determine whether there was QS insufficient subspecies infective for humans, and to identify the relations between specific infection types and virulence factors.