Associations between serum hepcidin level, FGF-21 level and oxidative stress with arterial stiffness in CAPD patients

Ulu S. M., Yuksel S., ALTUNTAŞ A., Kacar E., Ahsen A., Altug A., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.46, no.12, pp.2409-2414, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 12
  • Publication Date: 2014
  • Doi Number: 10.1007/s11255-014-0753-7
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2409-2414
  • Süleyman Demirel University Affiliated: Yes

Abstract

Patients on continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis have accelerated atherosclerosis associated with an increase in cardiovascular morbidity and mortality. Atherosclerosis is associated with increased arterial stiffness (AS), endothelial dysfunction and elevated oxidative stress (OS) and inflammation. We aimed to investigate the relationship between oxidative stress status, arterial stiffness, hepcidin and fibroblast growth factor-21 (FGF-21) levels in CAPD patients.