Magnetic resonance imaging and diffusion-weighted imaging in methylmalonic acidemia

Yesildag A., Ayata A., Baykal B., Koroglu M., Yildiz H., Oral B., ...More

ACTA RADIOLOGICA, vol.46, no.1, pp.101-103, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1080/02841850510020888
  • Journal Name: ACTA RADIOLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.101-103
  • Süleyman Demirel University Affiliated: No


Methylmalonic acidemia (MMA) is an inborn disorder of amino acid metabolism, often presenting with neurological symptoms. We present the results of magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) of the brain in a 16-month-old male patient with classic neurological and laboratory findings for MMA. MRI demonstrated the hyperintensity within globi pallidi both on T2-weighted image and DWI during the acute episode of metabolic acidosis.