TGF-beta (transforming growth factor-beta) and signal transduction: Medical education


Soyoez M., ÖZÇELİK N.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.27, sa.3, ss.426-433, 2007 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 27 Konu: 3
  • Basım Tarihi: 2007
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Sayfa Sayıları: ss.426-433

Özet

The transforming growth factor-beta (TGF-beta) family comprising a large group of extracellular growth factors controls the development of the organism. TGF-beta family members consists of a large number of structurally related polypeptide growth factors, each capable of regulating a fascinating array of cellular processes including cell proliferation, differentiation, motility, adhesion, and death. TGF-beta and related factors play a prominent role in the development, homeostasis and repair of virtually all tissues in organisms.