TGF-beta (transforming growth factor-beta) and signal transduction: Medical education

Soyoez M., ÖZÇELİK N.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.27, no.3, pp.426-433, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2007
  • Journal Name: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.426-433
  • Süleyman Demirel University Affiliated: Yes

Abstract

The transforming growth factor-beta (TGF-beta) family comprising a large group of extracellular growth factors controls the development of the organism. TGF-beta family members consists of a large number of structurally related polypeptide growth factors, each capable of regulating a fascinating array of cellular processes including cell proliferation, differentiation, motility, adhesion, and death. TGF-beta and related factors play a prominent role in the development, homeostasis and repair of virtually all tissues in organisms.