Characterization of Volatile Compounds of Eleven Achillea Species from Turkey and Biological Activities of Essential Oil and Methanol Extract of A. hamzaoglui Arabaci & Budak

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Turkmenoglu F. P., AĞAR O. T., AKAYDIN G., HAYRAN K. M., Demirci B.

MOLECULES, vol.20, no.6, pp.11432-11458, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.3390/molecules200611432
  • Journal Name: MOLECULES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.11432-11458
  • Keywords: Achillea, Achillea hamzaoglui, Asteraceae, essential oil, antioxidant, antimicrobial, GC-MS, principal components analysis (PCA), hierarchical cluster analysis (HCA), VITRO ANTIMICROBIAL ACTIVITIES, CHEMICAL-COMPOSITION, MILLEFOLIUM L., TRADITIONAL MEDICINE, SCHISCHKINII SOSN., FOLK MEDICINE, TERETIFOLIA, ANTIOXIDANT, VARIABILITY, ASTERACEAE
  • Süleyman Demirel University Affiliated: Yes


According to distribution of genus Achillea, two main centers of diversity occur in S.E. Europe and S.W. Asia. Diversified essential oil compositions from Balkan Peninsula have been numerously reported. However, report on essential oils of Achillea species growing in Turkey, which is one of the main centers of diversity, is very limited. This paper represents the chemical compositions of the essential oils obtained by hydrodistillation from the aerial parts of eleven Achillea species, identified simultaneously by gas chromatography and gas chromatography-mass spectrometry. The main components were found to be 1,8-cineole, p-cymene, viridiflorol, nonacosane, -bisabolol, caryophyllene oxide, -bisabolon oxide A, -eudesmol, 15-hexadecanolide and camphor. The chemical principal component analysis based on thirty compounds identified three species groups and a subgroup, where each group constituted a chemotype. This is the first report on the chemical composition of A. hamzaoglui essential oil; as well as the antioxidant and antimicrobial evaluation of its essential oil and methanolic extract.