Product operator theory was often used to describe analytically multipulse NMR experiments for weakly coupled spin systems. in this study first we introduce the descriptions of subspectral editing with a multiple quantum trap NMR spectra for ISn (I = 1/2, S = 5/2 with n = 1, 2, 3) spin systems by using product operator formalism. These theoretical investigations lead us to form the general expressions for the intensities of the spin -1/2 nuclei coupled to the nuclei with spin greater than or equal to 5/2. The obtained results can be used for the spectral editing in both liquid-state and solid-state NMR experiments. Furthermore, in order to satisfy the obtained analytical expressions for signal intensities we add the presentation of analytically description of subspectral editing with a multiple quantum trap sequence for weakly coupled IS (I = 1/2, S = 7/2) spin system.