Topical Application of Tacrolimus Prevents Epidural Fibrosis in a Rat Postlaminectomy Model: Histopathological and Ultrastructural Analysis

İSMAİLOĞLU Ö. , Albayrak B., Gulsen I., TANRIÖVER G., DEMİR N.

TURKISH NEUROSURGERY, vol.21, no.4, pp.630-633, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.5137/1019-5149.jtn.4954-11.1
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.630-633


AIM: Postlaminectomy epidural fibrosis is the formation of scar tissue over the dura mater following posterior spinal surgery. This devastating complication is responsible for the substantial amount of failed back syndromes.