An important factor for achieving the desired yield level in agriculture production is effective nitrogen fertilization in terms of sustainable yield and environment quality. This research was conducted to determine the nitrogen efficiency of some bread wheat varieties at Suleyman Demirel University research and experimental area in the periods 2010-11 and 2011-12 under rainfed conditions. Four bread wheat varieties (Adana-99, Bezostaja-1, Esperia and Tosunbey) in the experiment were compared using three different N doses (0, 75 and 125 kg ha(-1) N). Nitrogen doses affected to all in examined parameters, except apparent recovery fraction. 125 kg ha(-1) N dose increased the yield, protein content and the response index while value of agronomic and physiological activities decreased compared to 75 kg ha(-1) N dose. The highest grain yield in the first year was obtained from Esperia cultivar with 2619 kg ha(-1) and Adana-99 cultivar with 2111 kg ha-1 in the second year. The highest response index was found in Adana-99 cultivar in the both years.