Pakistan and neighbourhood experience numerous earthquakes, most of which result in damaged or collapsed buildings and loss of life that also affect the economy adversely. On 29 October, 2008, an earthquake of magnitude 6.5 occurred in Ziarat, Quetta Region, Pakistan which was followed by more than 400 aftershocks. Many villages were completely destroyed and more than 200 people died. The previous major earthquake was in 2005, known as the South Asian earthquake (M-w=7.6) occurred in Kashmir, where 80 000 people died. Inadequate building stock is to be blamed for the degree of disaster, as the majority of the buildings in the region are unreinforced masonry low-rise buildings. In this study, seismic vulnerability of regionally common unreinforced masonry low-rise buildings was investigated using probabilistic based seismic safety assessment. The results of the study showed that unreinforced masonry low-rise buildings display higher displacements and shear force. Probability of damage due to higher displacements and shear forces can be directly related to damage or collapse.