This study was carried out to determine the nourishment preference and life table of the larvae and adults of Leptinotarsa decemlineata on the potato varieties of Agria, Pasinler, Marfona, Granola and Caspar. While the longest development duration in L. decemlineata was observed on the Granola variety, the shortest one was detected on the Caspar variety. The highest egg mortality in the Colorado potato beetle occurred on the Marfona variety, while the lowest mortality occurred on the Pasinler variety. The total mortality of immature stages of L. decemlineata was the highest on the Marfona variety and the lowest was on the Caspar variety. The highest larval mortalities were observed in the first larval stages. The highest daily fecundities on potato varieties were on the Granola variety and the highest total fecundities were on the Pasinler variety. However, the lowest values for both characteristics were on the Agria variety. The descending order of intrinsic rates of increase was Pasinler, Caspar, Agria, Marfona and Granola potato varieties. The highest net reproductive rates were on the Caspar variety and the lowest rates were on the Granola variety. The generation time was the longest in the Caspar variety and the shot-test in the Pasinler variety. The Colorado potato beetle showed the least performance on the Marfona potato variety when considering the mortality of eggs and immature stages, total fecundity and net reproductive rate.