Today there are a set of numerical model studies concerning mobile phones, wireless devices and human brain interaction; however since it is not feasible to conduct experiments on humans it becomes a necessity to simulate biological tissues. In the present study temperature rise created by 900 MHz-1800 MHz and 2450 MHz frequency electromagnetic radiations on human brain tissue has been searched by using brain-tissue phantom model. Three distinctive brain-equivalent tissues have been prepared and by paying heeds to the mixture ratios, their electrical features have been specified. At this point it has been detected that frequency is a critical factor. Phantom volume of 900 and 1800 MHz frequencies, depending on the volume skin effect, can be affected to a certain degree from the exposure. However an exposure of 2450 MHz cannot exhibit the desired level of temperature rise inside phantom liquid. This may be attributed to the skin effect in this frequency.