Granulosa cell tumor and concurrent endometrial cancer with F-18-FDG uptake

GÜNYELİ İ., BOZKURT K. K. , Yalcin Y., Tatar B., Cerci S. S. , ERDEMOĞLU E.

HELLENIC JOURNAL OF NUCLEAR MEDICINE, vol.17, no.2, pp.153-155, 2014 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2014
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.153-155


The findings and the role of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) for the diagnosis of ovarian granulosa cell tumor (OG) are described. We present the pre-operative findings of F-18-FDG PET/CT scan of a case of OG concurrent with endometrium cancer and endometrial hyperplasia, which revealed a 48mm mass demonstrating mild increased metabolic activity on the right ovary. Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. Frozen and paraffin-enbeded sections showed an encapsulated OG. There were few mitoses. There was concurrent atypical endometrial hyperplasia. In conclusion, we reported a case of an encapsulated OG, which showed mild uptake of the F-18-FDG with concurrent endometrial cancer. There has been only one report of F-18-FDG findings in primary ovarian granulosa cell tumor, similar to ours.