Polyoxometalate decorated graphene oxides sheets for simultaneous non-enzymatic electrochemical detection of biomolecules
Diamond and Related Materials, cilt.154, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 154
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/j.diamond.2025.112148
- Dergi Adı: Diamond and Related Materials
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
- Anahtar Kelimeler: Ascorbic acid, Electrocatalyst, Graphene oxides, Polyoxometalate, Sensing, Uric acid
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
A novel Wells-Dawson type Polyoxometalates (POM) in combination with graphene oxide (GO) has been developed as a non-enzymatic electrochemical sensor for the detection of ascorbic acid and uric acid. The electrochemical detection of these biomolecules is crucial in biomedical analysis, offering high sensitivity, selectivity, and rapid detection. This method significantly contributes to physiology, disease diagnostics, therapeutic monitoring, and the advancement of portable biosensor technologies. As prepared POM@GO composite was characterized using various techniques including X-ray diffraction crystallography (XRD), Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and energy dispersive x-ray (EDX) spectroscopy to confirm the functional groups, crystal structure, morphology and elemental composition, respectively. Uniformly dispersed POM over conductively efficient GO boosted the catalytic performance synergies via active site and enlarge surface area provided by the POM and GO, respectively. As fabricated composite improved sensitivity towards individual and simultaneous electrochemical detection of ascorbic acid and uric acid. POM@GO over glassy carbon electrode showed a higher sensitivity of 10.24 μAcm−2 mM−1 and 5.27 μAcm−2 mM−1, lower detection limit of 46 μM and 47 μM and a linear range of up to 1.5 mM for AA and UA, respectively.