Natural organic matter (NOM) removal efficiency of natural and waste materials used both as the catalyst and as the adsorbent was investigated altogether. The influence of important parameters such as temperature, presence of radical scavengers and NOM source on the efficiency of catalytic ozonation was examined. Moreover, the various processes such as (catalytic hydrogen peroxide oxidation, hydrogen peroxide only, adsorption only, single ozonation and catalytic ozonation processes) were compared. According to experimental results, the application of iron-coated pumice to the ozonation process enhanced the efficiency of NOM removal when compared with single ozonation and adsorption only. However, steel slag and original red mud particles from waste materials did not exhibit any catalytic activity for NOM degradation on catalytic ozonation process. The addition of tert-butanol remarkably decreased the removal efficiency of NOM in iron-coated pumice catalyzed ozonation, which suggested that NOM degradation follows the mechanism of hydroxyl radical oxidation. The obtained NOM removal was greater in the humic acid solution than in the low specific UV absorbance natural water by catalytic ozonation. However, approximately 60% UV absorbance removals were achieved by iron-coated catalyzed ozonation in natural waters. In low catalyst dose, the catalytic ozonation showed better performance for removal efficiency of NOM than the catalytic hydrogen peroxide oxidation did.