CeSe decorated graphene oxides nanohybrid anchored CNTs Fiber: A flexible microelectrode for biomolecules dual detection
Microchemical Journal, cilt.227, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 227
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.microc.2026.118673
- Dergi Adı: Microchemical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, Chimica, Index Islamicus, Academic Search Ultimate (EBSCO), Engineering Source (EBSCO)
- Anahtar Kelimeler: Ascorbic acid, Cerium selenide, CNTs fiber, Electrochemical sensing, Graphene, Uric acid
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
The simultaneous detection of structurally analogous electroactive biomolecules with intrusive facts remains a critical challenge in the development of intelligent biosensing interfaces. In this study, a flexible electrochemical sensor based on cerium selenide-graphene oxide nanohybrid modified carbon nanotube fiber was developed for simultaneous detection of ascorbic acid and uric acid. The sensor leverages the switchable nature of cerium, and high surface area of graphene oxide. Physicochemical characterizations confirmed successful integration and uniform distribution of cerium selenide nanoparticle over the surface of graphene oxide sheets. Electrochemical evaluation displayed, well-separated oxidation peaks at 0.12 V and 0.28 V for ascorbic acid and uric acid, respectively vs. silver/ silver chloride electrode, with a charge transfer coefficient of ∼0.76 for both analytes, underscoring efficient electrons transfer kinetics. The sensor demonstrated extensive linear response ranges (50 μM to mM-1.8 mM), with high sensitivities of 0.50 mAcm−2 mM−1for ascorbic acid and 0.44 mAcm−2 mM−1 for uric acid and low detection limits of 60 μM and 68 μM, respectively. Cerium selenide-graphene oxide nanohybrid modified carbon nanotube fiber electrode retained stability and reproducibility during repeated cycles. The fabricated electrode offers substantial promise for next generation wearable and point of care diagnostics in real time applications.