Investigation of GLUT1, HIF1 alpha and TBX21 Gene Polymorphisms in Laryngeal Cancer

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Uslu C., TÜZ M., YASAN H., OKUR E.

TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY-TURK OTORINOLARENGOLOJI ARSIVI, vol.56, no.2, pp.70-74, 2018 (ESCI)

• Publication Type: Article / Article
• Volume: 56 Issue: 2
• Publication Date: 2018
• Doi Number: 10.5152/tao.2018.3177
• Journal Name: TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY-TURK OTORINOLARENGOLOJI ARSIVI
• Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
• Page Numbers: pp.70-74
• Süleyman Demirel University Affiliated: Yes

Abstract

Objective: We aimed to investigate the association of the frequency of three single-nucleotide polymorphisms [glucose transporter isoform 1 (GLUT1) reference single-nucleotide polymorphism (rs) 710218, hypoxia-inducible factor 1 alpha (HIF1 alpha) rs11549465, and T-box transcription factor protein 21 (TBX21) rs17250932], which have been proved to be related with various benign and malignant diseases, with the development of laryngeal cancer and its size and grade.