Strict heart rate control attenuates prothrombotic state and platelet activity in patients with non-valvular permanent atrial fibrillation

ERDOGAN D., UYSAL B. A. , AKSOY F. , KAYA S. , ICLI A., CEYHAN B. M. , ...More

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, vol.56, no.3, pp.219-229, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.3233/ch-131710
  • Title of Journal : CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
  • Page Numbers: pp.219-229

Abstract

BACKGROUND: The underlying mechanisms of increased risk of thrombo-embolism in atrial fibrillation (AF) are not completely understood; however, substantial evidence supports that AF is associated with a prothrombotic state. Accordingly, we hypothesized that strict rate control could attenuate platelet activity and thrombotic state in patients with non-valvular AF.