Transient focal cerebral ischemia-induced neurogenesis in the dentate gyrus of the adult mouse

Tureyen K., Vemuganti R., Sailor K., Bowen K., Dempsey R.

JOURNAL OF NEUROSURGERY, cilt.101, sa.5, ss.799-805, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 101 Konu: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.3171/jns.2004.101.5.0799
  • Sayfa Sayıları: ss.799-805


Object. Throughout the life of a mammal, new neurons are produced each day from resident progenitor cells located in the hippocampal dentate gyrus (DG). The availability of transgenic and knockout mice enables the evaluation of specific molecular mediators of this phenomenon. To facilitate such studies the authors characterized the proliferation, survival, and maturation of progenitor cells in the DG of adult mice following transient focal cerebral ischemia.