Carbon-carbon bond formation catalyzed by PEPPSI Pd-NHC


Akkoc S. , İLHAN İ. Ö. , GÖK Y., Kayser V.

INORGANICA CHIMICA ACTA, vol.461, pp.52-56, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 461
  • Publication Date: 2017
  • Doi Number: 10.1016/j.ica.2017.01.025
  • Title of Journal : INORGANICA CHIMICA ACTA
  • Page Numbers: pp.52-56
  • Keywords: N-Heterocyclic carbene, PEPPSI complex, Palladium, Suzuki-Miyaura cross-coupling reaction, Catalyst, COMPLEXES SYNTHESIS, COUPLING REACTIONS, SILVER, SALTS

Abstract

Five new palladium complexes were efficiently synthesized from the reaction of benzimidazolium salts, potassium carbonate (K2CO3) and palladium chloride (PdCl2) in pyridine (for 3-5) or 3-chloropyridine (for 6 and 7). The synthesized complexes were characterized and tested in Suzuki-Miyaura cross-coupling reaction as catalysts. In the presence of catalysts 3-7, biaryl products were obtained in moderate yields when phenylboronic acid was used as boronic acid derivative. However, the coupling of thianaphthene-2-boronic acid with 1-chloro-4-nitrobenzene generated low yields although a longer period of time was used in comparison to the coupling of phenylboronic acid with aryl chlorides. (C) 2017 Elsevier B.V. All rights reserved.