An evaluation of normal saline and taurolidine on intra-abdominal adhesion formation and peritoneal fibrinolysis


TARHAN Ö. R., BARUT İ., SEZİK M.

JOURNAL OF SURGICAL RESEARCH, cilt.144, sa.1, ss.151-157, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 144 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jss.2007.09.006
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.151-157
  • Anahtar Kelimeler: peritoneal adhesions, peritoneal fibrinolysis, normal saline, taurolidine, tPA, tPA activity, PAI-1, tPA/PAI-1 complex, hydroxyproline, INTRAPERITONEAL TUMOR-GROWTH, POSTOPERATIVE ADHESIONS, PLASMINOGEN-ACTIVATOR, CLINICAL-SIGNIFICANCE, SURGICAL TRAUMA, PELVIC-SURGERY, RAT MODEL, PREVENTION, ETIOLOGY, TISSUE
  • Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Background. Intraoperative lavage with normal saline or taurolidine solutions is commonly used in abdominal surgery. For this purpose, normal saline and taurolidine, which may modify the intrinsic fibrinolytic activity of the peritoneum by breaking the peritoneal adhesions, are frequently used. We aimed to evaluate how normal saline and taurolidine affect peritoneal fibrinolysis and adhesion formation.