In the study it was aimed to examine and determine some anatomical features of Lycopersicon esculentum Mill. cv. Ceren and Lycopersicon esculentum Mill. cv. Panda varieties cultivated under hydroponic condition in greenhouse in Sanhurfa, Turkey. Cross sections were cut from the root, stem and leaf by microtome and examined by light microscopy. The results were photographed. Biometric measurements of some tissues were performed. The roots of the plants are surrounded by 1 layered epidermis formed by big and small cells. Vascular bundle gathered in the centre. Stems are formed 1 layered epidermis, 1-2 layered chlorenchyma, 3-4, 4-5 layered collenchyma and 3-4, 4-5 layered parenchymatic tissues. Vascular bundles are bicollateral. Pith is parenchymatic. Stomate, epidermal hair and glandular hair are observed. Leaves are bifacial and amphistomatic Mesophyll is formed by 1 layered palisade parenchyma and 2-3 layered spongy parenchyma. Big vascular bundle is bicollateral and small vascular bundle is collateral. They have epidermal and glandular hairs. As a result, some basic anatomical features examined showed that cv. Ceren and cv. Panda are convenient for cultivation under hydroponic system.The data obtained will contribute to soilless agricultural cultivation in the province and will pave the way for similar scientific studies.