The Importance of Prostate-Specific Membrane Antigen Expression in Carotid Body Paragangliomas


YASAN H. , KUMBUL Y. Ç. , ÇİRİŞ İ. M. , SİVRİCE M. E. , OKUR E.

TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY, vol.59, no.3, pp.203-209, 2021 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.4274/tao.2021.2021-3-17
  • Title of Journal : TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY
  • Page Numbers: pp.203-209
  • Keywords: Carotid body, carotid body tumor, immunohistochemistry, paraganglioma, prostate-specific membrane antigen, surgery, histopathology, DIAGNOSIS, HEAD, NECK

Abstract

Objective: Prostate-specific membrane antigen (PSMA) is a transmembrane protein expressed in prostate cancer. It is, however, also expressed in the neovasculature of some non-prostatic solid tumors. Carotid body paragangliomas (CBPs) are highly vascular neoplasms. In this study, we aimed to investigate the possible role of PSMA expression in CBPs. 'There are no studies in the literature that report to have investigated the relationship between PSMA and CBPs.