Elevated mean platelet volume is associated with impaired coronary microvascular function in patients with idiopathic dilated cardiomyopathy

ERDOĞAN D., TAYYAR S., İÇLİ A., UYSAL B. A. , VAROL E., Ozaydin M., ...More

PLATELETS, vol.23, no.3, pp.177-183, 2012 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.3109/09537104.2011.611273
  • Journal Name: PLATELETS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.177-183


Attenuated coronary flow reserve (CFR) has been reported in patients with idiopathic dilated cardiomyopathy (IDC). On the other hand increased platelet activity has been demonstrated in patients with congestive heart failure and left ventricular dysfunction. Accordingly, we aimed to investigate whether mean platelet volume (MPV) is increased in patients with IDC and increased MPV correlates with the degree of coronary microvascular dysfunction.