JOURNAL OF PERIODONTOLOGY, vol.83, no.11, pp.1425-1431, 2012 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF PERIODONTOLOGY
Aggressive periodontitis, cytokines, gingival crevicular fluid, periodontal diseases, BONE DESTRUCTION, TH17 PATHWAY, IL-17, CYTOKINES, CELLS, INFLAMMATION, NEUTROPHILS, PHAGOCYTOSIS, PATHOGENESIS, EXPRESSION
Background: The balance (ratio) of anti-inflammatory and proinflammatory cytokines is thought to play an important role in the pathogenesis of chronic periodontitis. Moreover, the imbalance of anti-inflammatory/proinflammatory cytokines may modulate disease progression in aggressive periodontitis (AgP). This study aims to investigate the levels of interleukin (IL)-11 and IL-17 and their ratio in gingival crevicular fluid (GCF) in patients with AgP.