Women employment in Turkey is at the back rows in OECD countries, European and Middle Eastern countries. As women employment rates change between 62% and 64% in OECD countries and European Union this rate is about 27% in Turkey. The trend related to women entrepreneurship is nearly the same. In 2003 women entrepreneurs were 4% and self-employed women were 14% of all when compared to the men. In fact in 1980s and in 1990s women entrepreneurship was supported. Because entrepreneurship was considered a key factor in development in parallel with the adaptation of neo-liberal politics after the government had left the market and women entrepreneurship was supported in this context. Women entrepreneurship was accepted one of the ways of leaving out the economic crisis and increasing women employment under the effects of subsidies obtained by European Comission especially in 2000s. In spite of all these subsidies and policies the rate of women in employment was 30.3% and the rate of self employed women was 8% according to the figures released in 2015 by Turkish Bureau of Statistics. In this paper gender dimension of women entrepreurship and the role of entrepreneurship in women empowerment in Turkey is dealt with. Women employment is questioned in terms of effects of globalization on local economy, domestic relations, socio-economic and cultural dimensions of it, considering experiences of Turkey and other countries. Lastly determinants of women empowerment is evaluated according to a research carried out on sucessful women entrepreneurs in the West Mediterranean Region of Turkey.