Fingolimod against endotoxin-induced fetal brain injury in a rat model

YAVUZ, And; SEZİK, Mekin; Ozmen, Ozlem; AŞCI, Halil

doi:10.1111/jog.13444

Fingolimod against endotoxin-induced fetal brain injury in a rat model

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YAVUZ A., SEZİK M. , Ozmen O., AŞCI H.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, vol.43, no.11, pp.1708-1713, 2017 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 43 Issue: 11
Publication Date: 2017
Doi Number: 10.1111/jog.13444
Title of Journal : JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
Page Numbers: pp.1708-1713

Abstract

AimFingolimod is a sphingosine-1-phosphate receptor modulator used for multiple sclerosis treatment and acts on cellular processes such as apoptosis, endothelial permeability, and inflammation. We hypothesized that fingolimod has a positive effect on alleviating preterm fetal brain injury.