T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer


Obradovic A. Z., Dallos M. C., Zahurak M. L., Partin A. W., Schaeffer E. M., Ross A. E., ...More

CLINICAL CANCER RESEARCH, vol.26, no.13, pp.3182-3192, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 13
  • Publication Date: 2020
  • Doi Number: 10.1158/1078-0432.ccr-19-3372
  • Journal Name: CLINICAL CANCER RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, EMBASE, Gender Studies Database, MEDLINE
  • Page Numbers: pp.3182-3192
  • Süleyman Demirel University Affiliated: Yes

Abstract

Purpose: Previous studies suggest that androgen deprivation therapy (ADT) promotes antitumor immunity in prostate cancer. Whether a vaccine-based approach can augment this effect remains unknown.