T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Obradovic, Aleksandar; Dallos, Matthew; Zahurak, Marianna; Partin, Alan; Schaeffer, Edward; Ross, Ashley; Allaf, Mohamad; Nirschl, Thomas; Liu, David; Chapman, Carolyn; O'Neal, Tanya; Cao, Haiyi; Durham, Jennifer; Guner, Gunes; Baena-Del Valle, Javier; Ertunc, Onur; De Marzo, Angelo; Antonarakis, Emmanuel; Drake, Charles

doi:10.1158/1078-0432.ccr-19-3372

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Atıf İçin Kopyala

Obradovic A. Z. , Dallos M. C. , Zahurak M. L. , Partin A. W. , Schaeffer E. M. , Ross A. E. , ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.26, ss.3182-3192, 2020 (SCI İndekslerine Giren Dergi)

Cilt numarası: 26 Konu: 13
Basım Tarihi: 2020
Doi Numarası: 10.1158/1078-0432.ccr-19-3372
Dergi Adı: CLINICAL CANCER RESEARCH
Sayfa Sayıları: ss.3182-3192

Özet

Purpose: Previous studies suggest that androgen deprivation therapy (ADT) promotes antitumor immunity in prostate cancer. Whether a vaccine-based approach can augment this effect remains unknown.