T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Obradovic, Aleksandar; Dallos, Matthew; Zahurak, Marianna; Partin, Alan; Schaeffer, Edward; Ross, Ashley; Allaf, Mohamad; Nirschl, Thomas; Liu, David; Chapman, Carolyn; O'Neal, Tanya; Cao, Haiyi; Durham, Jennifer; Guner, Gunes; Baena-Del Valle, Javier; Ertunc, Onur; De Marzo, Angelo; Antonarakis, Emmanuel; Drake, Charles

doi:10.1158/1078-0432.ccr-19-3372

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Obradovic A. Z., Dallos M. C., Zahurak M. L., Partin A. W., Schaeffer E. M., Ross A. E., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.26, sa.13, ss.3182-3192, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 13
Basım Tarihi: 2020
Doi Numarası: 10.1158/1078-0432.ccr-19-3372
Dergi Adı: CLINICAL CANCER RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, EMBASE, Gender Studies Database, MEDLINE
Sayfa Sayıları: ss.3182-3192
Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Purpose: Previous studies suggest that androgen deprivation therapy (ADT) promotes antitumor immunity in prostate cancer. Whether a vaccine-based approach can augment this effect remains unknown.