T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer


Obradovic A. Z. , Dallos M. C. , Zahurak M. L. , Partin A. W. , Schaeffer E. M. , Ross A. E. , ...More

CLINICAL CANCER RESEARCH, vol.26, no.13, pp.3182-3192, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 13
  • Publication Date: 2020
  • Doi Number: 10.1158/1078-0432.ccr-19-3372
  • Title of Journal : CLINICAL CANCER RESEARCH
  • Page Numbers: pp.3182-3192

Abstract

Purpose: Previous studies suggest that androgen deprivation therapy (ADT) promotes antitumor immunity in prostate cancer. Whether a vaccine-based approach can augment this effect remains unknown.