Regression of endometrial explants in a rat model of endometriosis treated with melatonin

GÜNEY, Mehmet; Oral, Hilmi; KARAHAN, Nermin; Mungan, Tamer

doi:10.1016/j.fertnstert.2007.04.023

Regression of endometrial explants in a rat model of endometriosis treated with melatonin

GÜNEY M., Oral B. , KARAHAN N. , Mungan T.

FERTILITY AND STERILITY, vol.89, no.4, pp.934-942, 2008 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 89 Issue: 4
Publication Date: 2008
Doi Number: 10.1016/j.fertnstert.2007.04.023
Title of Journal : FERTILITY AND STERILITY
Page Numbers: pp.934-942

Abstract

Objective: To determine the antioxidant, antiinflammatory, and immunomodulatory effects of melatonin on endometrial explants, the distribution of cyclooxygenase-2 (COX-2), the activity of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), and levels of malondialdehyde (MDA) in the rat endometriosis model.