Alpha lipoic acid attenuates inflammatory response during extracorporeal circulation


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Uyar I. S. , Onal S., Akpinar M. B. , Gonen I., Sahin V., Uguz A. C. , ...More

CARDIOVASCULAR JOURNAL OF AFRICA, vol.24, no.8, pp.322-326, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.5830/cvja-2013-067
  • Title of Journal : CARDIOVASCULAR JOURNAL OF AFRICA
  • Page Numbers: pp.322-326

Abstract

Aim: Extracorporeal circulation (ECC) of blood during cardiopulmonary surgery has been shown to stimulate various pro-inflammatory molecules such as cytokines and chemokines. The biochemical oxidation/reduction pathways of alpha-lipoic acid suggest that it may have antioxidant properties.