Hepatitis-B and hepatitis-C seropositivity rates in pregnancy in ısparta province


Türk Alman Jinekoloji Kongresi, Girne, Cyprus (Kktc), 27 March - 30 April 2018, pp.57

  • Publication Type: Conference Paper / Summary Text
  • City: Girne
  • Country: Cyprus (Kktc)
  • Page Numbers: pp.57
  • Süleyman Demirel University Affiliated: Yes



Hepatitis-B and hepatitis-C seropositivity rates in pregnancy in ısparta province

Orhan Akpınar1, Veysel Atilla Ayyıldız2Fatih Akkuş3
1Suleyman Demirel University Health Sciences Institute Departmant of Medical Microbiology,Isparta, Turkey
2Suleyman Demirel University School of Medicine Departmant of Radiology, Isparta, Turkey
3Isparta State (City) Hospital Departmant of Gynecology and Obstetrics, Isparta, Turkey

AIM: Perinatal infection is the main way of transmission in high endemic countries, while horizontal infestation in early childhood is the most common transmission way in medium endemic countries. Newborn transmission from an infected mother can rarely occur during pregnancy, during or after birth. Hepatitis-B and Hepatitis-C viruses are viruses that can infect with infected body fluids. Moreover, chronic hepatitis B or C virus infection is the most important risk factor for the development of hepatocellular carcinoma. In this study, it was aimed to investigate the seroprevalence of hepatitis B and hepatitis C antibodies in pregnant women living in Isparta and its region.
MATERIALS-METHODS: HBsAg and anti-HCV results of pregnancies who applied for routine pregnancy follow-up to Isparta Obstetrics and Pediatrics Hospital, Obstetrics and Gynecology Polyclinic between January 2013 and December 2013 were retrospectively screened. Serological tests were studied using macro ELISA. Data for statistical evaluations were transferred to the computer in SPSS 18 statistical package program, frequency, percentage, mean ± standard deviations were calculated in statistical analyzes.
RESULTS: 4987 blood samples for HBsAg and 4632 blood samples for anti-HCV was evaluated. Results of 4987 cases; HbsAg was detected in 63 patients (1.3%), in 14 patient (0.3%) of 4632 cases anti-HCV seropositivity was detected (Table 1).
When the cases were examined according to age groups, the highest age group was 20-30 in both groups, while the least age group was 36-40 years (Table 2).
CONCLUSION: Hepatitis-B and Hepatitis-C viruses are viruses that can infect with infected body fluids. It is important to know the frequency of infection in pregnant women to protect the newborn. Anti-HBs and anti-HCV positivity rates that we found in our study were found to be similar to the positivity rates determined in the general population in our country. When these ratios are evaluated, especially in the pregnant and reproductive age groups; planning and effective implementation of screening and vaccination programs in terms of hepatitis B will be an appropriate approach in terms of community health. HbsAg should be considered in all pregnant women in blood samples. However, it may be worth investigating anti-HCV in pregnancies at risk. Early diagnosis of the disease will provide important advantages for vaccination and treatment as it will protect the patient from future complications. In addition, these viruses can infect the baby to be born vertically or horizontally, and can create long-term health risks for the baby. It is important to know the frequency of chronic HBV infection in pregnancy in order to protect the newborn from the risks of HBV infection. Knowing HBsAg and anti-HCV positivity before intervention in patients; physicians and other health care providers to take preventive measures against disease transmission

Keywords: HBV, HCV, pregnancy, seroprevalence

Sunum Detayları:  Sözlü Bildiri Numarası: OP-095
Sunum Tarihi: 29 Nisan 2018 Pazar
Sunum Saati: 16:10 - 16:15
Salon: Hall 5