Green and Chamomile Teas, but not Acarbose, Attenuate Glucose and Fructose Transport via Inhibition of GLUT2 and GLUT5

Villa-Rodriguez J. A. , Aydin E. , Gauer J. S. , Pyner A., Williamson G., Kerimi A.

MOLECULAR NUTRITION & FOOD RESEARCH, vol.61, no.12, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 12
  • Publication Date: 2017
  • Doi Number: 10.1002/mnfr.201700566
  • Title of Journal : MOLECULAR NUTRITION & FOOD RESEARCH
  • Keywords: carbohydrates, flavonoids, polyphenols, sugar, tea, TYPE-2 DIABETES-MELLITUS, BRUSH-BORDER MEMBRANE, ENDOTHELIAL DYSFUNCTION, SUBSTRATE SELECTIVITY, DIETARY POLYPHENOLS, ALPHA-GLUCOSIDASE, SUGAR ABSORPTION, CACO-2 CELLS, TOLERANCE, EXPRESSION

Abstract

Scope High glycaemic sugars result in blood-glucose spikes, while large doses of post-prandial fructose inundate the liver, causing an imbalance in energy metabolism, both leading to increased risk of metabolic malfunction and type 2 diabetes. Acarbose, used for diabetes management, reduces post-prandial hyperglycaemia by delaying carbohydrate digestion.