Green and Chamomile Teas, but not Acarbose, Attenuate Glucose and Fructose Transport via Inhibition of GLUT2 and GLUT5

Villa-Rodriguez, Jose; Aydin, Ebru; Gauer, Julia; Pyner, Alison; Williamson, Gary; Kerimi, Asimina

doi:10.1002/mnfr.201700566

Green and Chamomile Teas, but not Acarbose, Attenuate Glucose and Fructose Transport via Inhibition of GLUT2 and GLUT5

Villa-Rodriguez J. A., Aydin E., Gauer J. S., Pyner A., Williamson G., Kerimi A.

MOLECULAR NUTRITION & FOOD RESEARCH, cilt.61, sa.12, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 61 Sayı: 12
Basım Tarihi: 2017
Doi Numarası: 10.1002/mnfr.201700566
Dergi Adı: MOLECULAR NUTRITION & FOOD RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: carbohydrates, flavonoids, polyphenols, sugar, tea, TYPE-2 DIABETES-MELLITUS, BRUSH-BORDER MEMBRANE, ENDOTHELIAL DYSFUNCTION, SUBSTRATE SELECTIVITY, DIETARY POLYPHENOLS, ALPHA-GLUCOSIDASE, SUGAR ABSORPTION, CACO-2 CELLS, TOLERANCE, EXPRESSION
Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Scope High glycaemic sugars result in blood-glucose spikes, while large doses of post-prandial fructose inundate the liver, causing an imbalance in energy metabolism, both leading to increased risk of metabolic malfunction and type 2 diabetes. Acarbose, used for diabetes management, reduces post-prandial hyperglycaemia by delaying carbohydrate digestion.