Levetiracetam Serum Concentrations in Pediatric Patients: Is There a Role in Clinical Decision Making?
ARCHIVES OF EPILEPSY, cilt.28, sa.1, ss.35-38, 2022 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 1
- Basım Tarihi: 2022
- Doi Numarası: 10.54614/archepilepsy.2022.77045
- Dergi Adı: ARCHIVES OF EPILEPSY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.35-38
- Anahtar Kelimeler: drug monitoring, epilepsy, levetiracetam, pediatric, DRUG-INTERACTIONS, PHARMACOKINETICS, EFFICACY
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Objective: Monitoring levetiracetam plasma concentration is not frequently used in clinical practice due to the linear pharmacokinetics of the drug and the absence of drug interactions. Nonetheless, some studies mention pharmacokinetic interactions of the drug and suggest drug level monitoring. This study was conducted to evaluate the effect of concomitant antiepileptics on levetiracetam plasma concentration in children and to determine the importance of drug plasma concentration in clinical follow-up.