Predictive value of oxidative, antioxidative, and inflammatory status for left ventricular systolic recovery after percutaneous coronary intervention for ST-segment elevation myocardial infarction.
Revista da Associacao Medica Brasileira (1992), cilt.68, sa.10, ss.1369-1375, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 68 Sayı: 10
- Basım Tarihi: 2022
- Doi Numarası: 10.1590/1806-9282.20220300
- Dergi Adı: Revista da Associacao Medica Brasileira (1992)
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
- Sayfa Sayıları: ss.1369-1375
- Anahtar Kelimeler: Ventricular dysfunction, Oxidants, Antioxidants, ST elevation myocardial infarction, EJECTION FRACTION, TASK-FORCE, ASSOCIATION, GUIDELINES, MANAGEMENT, STRESS, SOCIETY, OXIDANT, ARTERY, ESC
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
OBJECTIVE: This study aimed to evaluate the association between left ventricular ejection fraction recovery and the total oxidant status, total antioxidant capacity, and high-sensitivity C-reactive protein levels. METHODS: A total of 264 ST-elevation myocardial infarction patients were classified into two groups according to baseline and 6-month follow-up left ventricular systolic function: reduced and recovery systolic function. Predictors of the recovery of left ventricular ejection fraction were determined by multivariate regression analyses. RESULTS: Multivariable analysis indicated that oxidative status index, baseline left ventricular ejection fraction and peak creatine-kinase myocardial bundle level, and high-sensitivity C-reactive protein were independently associated with the decreased of left ventricular ejection fraction at 6-month follow-up. CONCLUSION: Oxidative stress and inflammation parameters were detrimental to the recovery of left ventricular ejection fraction in patients with ST-elevation myocardial infarction.