Spontaneous recovery of pancytopenia in an immunosuppressed patient infected with Parvovirus B19

SİRKECİ Ö., Sirkeci E., Kucukciloglu Y.

Clinica Terapeutica, vol.173, no.2, pp.104-106, 2022 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 173 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.7417/ct.2022.2402
  • Journal Name: Clinica Terapeutica
  • Journal Indexes: Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.104-106
  • Keywords: Azathioprine, Pancytopenia, Parvovirus B19, Spontaneous recovery
  • Süleyman Demirel University Affiliated: Yes


Copyright © Società Editrice Universo (SEU)Parvovirus B19 infection can be associated with a wide spectrum of clinical manifestations that mainly depends on the clinical background of the patient. Infection causes severe aplastic effects on bone marrow in immunosuppressive patients. Our patient was using Azathioprine for Crohn Disease when she admitted with malaise and fatigue laboratory tests revealed pancytopenia due to Parvovirus B19 infection. But contrary to expectations patients pancytopenia improved spontaneously without any treatment. Although intravenous immunoglobulin treatment is a safe approach waiting spontaneous recovery of bone marrow may be risky but another option.