This is a cross-sectional study that explores the effects of acculturation attitudes on the health-promoting behaviors of international students in Isparta, Turkey. The study was carried out in eight departments at Suleyman Demirel University. The sample comprised 138 students. The data were collected using three forms: the Data Form, the Health-Promoting Lifestyle Profile (HPLP) scale, and the Acculturation Attitudes Scale. Correlation analysis revealed a positive correlation between the mean HPLP scores and the mean acculturation attitude scores (r=0.321, p<0.001). It is important for health professionals working with international students to understand the interactions between acculturation attitude and health-promoting behavior.