The Relationship between Red Cell Distribution Width with Erythropoietin Resistance in Iron Replete Hemodialysis Patients

Afsar, Barış; Saglam, Mustafa; Yuceturk, Cetin; Agca, Erhan

doi:10.1016/j.ejim.2012.11.017

The Relationship between Red Cell Distribution Width with Erythropoietin Resistance in Iron Replete Hemodialysis Patients

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Afsar B., Saglam M., Yuceturk C., Agca E.

EUROPEAN JOURNAL OF INTERNAL MEDICINE, vol.24, no.3, 2013 (SCI-Expanded)

Publication Type: Article / Article
Volume: 24 Issue: 3
Publication Date: 2013
Doi Number: 10.1016/j.ejim.2012.11.017
Journal Name: EUROPEAN JOURNAL OF INTERNAL MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Süleyman Demirel University Affiliated: Yes

Abstract

Background: Recently, erythropoietin resistance (ER) has been shown to be related with cardiovascular and overall mortality in hemodialysis (HD) patients. Red blood cell distribution width (RDW) has also shown to be associated with cardiovascular and all cause mortality in general population. Thus in the current study we tested the hypothesis that RDW and erythropoietin resistance as determined by erythropoiesis stimulating agents (ESA) hyporesponsiveness index (EHRI) may be related with each other in iron replete HD patients.